1 TO 16 YEARS: Oral: -Usual dose: 0.5 mg/kg orally once a day at bedtime OR 0.25 mg/kg orally 2 times a day. A typical dose regime is 0.25 to 0.5 mg per pound or 0.5 to 1.0 mg/kg every 12 to 24 hours. The recommended dosage and duration of PEPCID for oral suspension in adults with normal renal function is shown in Table 1. Famotidine Oral Suspension Dosage and Administration Recommended Dosage in Adults The recommended dosage and duration of famotidine for oral suspension in adults with normal renal function is shown in Table 1. In a study examining the effect of famotidine on gastric pH and duration of acid suppression in pediatric patients, four pediatric patients ages 11 to 15 years of age using the oral formulation at a dose of 0.5 mg/kg, maintained a gastric pH . Use another famotidine formulation for pediatric patients weighing less than 40 kg. Famotidine (Pepcid) is an oral drug used to treat symptoms of acid reflux and heartburn. ChildrenUse and dose must be determined by your doctor. Use a leading zero if it applies. 3. Learn about side effects, warnings, dosage, and more. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. It is used to treat syndromes caused by lots of stomach acid. In a double-blind, randomized, treatment-withdrawal study, 35 pediatric patients < 1 year of age who were diagnosed as having gastroesophageal reflux disease were treated for up to 4 weeks with famotidine oral suspension (0.5 mg/kg/dose or 1 mg/kg/dose). (round the answer to the nearest tenth. Storage. Age 6 months to 11 years old. 0.5 mg/kg/dose PO twice daily (Max: 40 mg PO twice daily). Paediatric population: The efficacy and safety of famotidine in children have not been established. GERD: Oral: Suspension: Infants <3 months: 0.5 mg/kg/dose once daily for up to 8 weeks; if not . Safe pediatric dosages can be calculated from adult doses based on child's weight in kilograms. after dialysis; no supplement; PD: give 25% usual divided dose q24h; no supplement hepatic dosing [not defined] If you forget a dose of prescription famotidine, take the missed dose as soon as you remember it. . Famotidine and Renal Dosing. Department of Pediatrics, the recommended famotidine dosing regimen at th e Children's Medical Center at the University of Virginia is 0.4 mg/kg given PO or IV every 8 hours. Dosage in Renal Impairment To treat erosive esophagitis (heartburn): Adults and children weighing 40 kilograms (kg) or more20 milligrams (mg) 1 or 2 times per day, at the morning and at bedtime, or 40 mg once a day at bedtime for up to 12 weeks. NDC 55390-027-01, 20 mL multidose vial, individually boxed. . For oral use. Further sizeable placebo-controlled evaluations of histamine-2 receptor antagonists in infants with gastro-oesophageal reflux disease are warranted. The studies described in PRECAUTIONS, Pediatric Use suggest that the starting dose in pediatric patients 1 to 16 years of age is 0.25 mg/kg intravenously . Antiulcer medications: Mechanism of action, pharmacology, and side effects. Dose: 800 mg orally twice daily; Famotidine (Pepcid) 40 mg/5ml oral suspension. Dose: 150 . Generic Name: famotidine. Pediatric Drug Dosing Guidelines famotidine Famotidine is associated with QT interval prolongation, caution with other drugs or conditions associated with QT interval prolongation. Intravenous dosage: Children and Adolescents: 0.25 mg/kg/dose IV every 12 hours (Max: 40 mg/day) is recommended by the manufacturer. Famotidine was approved by the FDA in 1995, and is available either with or without a prescription. The Famotidine-Famotidine group received one dose of famotidine at 22:00 the evening before surgery and a second dose 60-90 min before the scheduled time of surgery. Dose: 0.5 mg/kg/day orally daily; Age 3 months to 16 years old. Common Trade Names: Pepcid, Pepcid AC; Adult Dosing Active duodenal ulcer. Adults20 milligrams (mg) every 6 hours. Famotidine EG dosing Usual Adult Dose for Duodenal Ulcer: Initial: Parenteral: 20 mg IV every 12 hours. Stress ulcers in the intensive care unit . Pepcid is available via injection, suspension or tablet. Dosage forms: TAB: 10 mg, 20 mg, 40 mg; SUSP: 40 mg per 5 mL; INJ: various duodenal ulcer, active [40 mg PO qhs x4-8wk] Alt: 20 mg PO bid or 20 mg IV q12h; Info: if unable to take PO may use IV short-term only Famotidine 0.5 mg/kg/dose (Max: 20 mg) (1 - 3mo)DAILY, (3mo)BID DAILY-BID Pharmacology, adverse reactions, warnings and side effects. PEPCID 20 and 40 mg tablets are not recommended for use in pediatric patients weighing less than 40 kg because these tablet strengths exceed the recommended dose for these patients [see Dosage and Administration (2.1)]. Pharmacology, adverse reactions, warnings and side effects. Use of famotidine in pediatric patients 1 to 16 years of age is supported by evidence from adequate and well-controlled studies of famotidine in adults, and by the . In people with normal renal function, famotidine is a . PEPCID SUSPENSION prescription and dosage sizes information for physicians and healthcare professionals. It is used to treat heartburn and sour stomach. Do not take famotidine if you: are allergic to any component of famotidine products; have a history of allergy to other H2-receptor . risk of CYP2C19 poor metabolizer); give before meals; may open cap, see PPI Administration Alternatives table. dose in Asian pts (incr. Famotidine for oral suspension is indicated in pediatric patients from birth to less than 1 year of age for the treatment of: GERD. Abacavir (Ziagen) 16mg/kg/day 100mg/tsp 2x/day Acetaminophen (Tylenol) 40-60mg/kg/day 160mg/tsp 6x/day Acetaminophen Infant Drops (Tylenol) 40-60mg/kg/day 80mg/0.8cc 6x/day Amantadine (Rimantadine) 10mg/kg/day 50mg/tsp 2x/day Ampicillin 60-100mg/kg/day 125mg/tsp 250mg/tsp 4x/day . Pediatric: CrCl 10-50: decrease dose 50% or give q24 hr, CrCl<10: give q36-48 hr; Hepatic Dosing. The recommended adult intravenous dose is 20 mg q 12 h. . It is available as both generic and brand drug (commonly known as Pepcid). Famotidine Injection 10 mg/mL, is a preserved, clear, colorless solution and is supplied as follows: NDC 55390-028-10, 4 mL two dose vial, carton of 10. Famotidine 10mg, calcium carbonate 800mg, magnesium hydroxide 165mg; chew tabs; cool mint- and berry blend-flavors. 1-17 years: 0.25 mg/kg IV q12hr or 0.5 mg/kg PO at bedtime; may increase to 1 mg/kg once daily at bedtime or 0.5 mg/kg twice daily for up to 8 weeks; not to exceed 40 mg/day. A possibly efficacious famotidine dose for infants is 0.5 mg/kg (frequency adjusted for age). maint. Find information on Famotidine (Pepcid) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Parenteral famotidine is typically given in a dose of 20 mg every 12 hours. This is because the strengths of these tablets are greater than the recommended dose for these children. Patients who took famotidine in this trial experienced a decrease of inflammation within the body and reported earlier alleviation of symptoms. this is a calculation for ONE dose & you give this ONE dose THREE times a day] Table 2: Recommended Maximum Dosage of Famotidine Tablets in Adults and Pediatric Patients 40 kg and Greater with Moderate and Severe Renal Impairment An alternate dosage regimen is 10 mg once daily. The FDA-approved product labeling recommends the following dosage adjustments in adult and pediatric patients 40 kg and more: Active DU or Active GU: CrCl 30 to 60 mL/minute: 20 mg once daily or 40 mg every other day. or diphenhydramine 50 mg i.m. . In adult patients with moderate (creatinine clearance <50 mL/min) or severe (creatinine clearance <10 mL/min) renal insufficiency, the elimination half-life of famotidine is increased. In this prospective, double-blind, controlled trial, 25 patients with urticaria of less than 72 h duration were randomized to receive a single dose of either famotidine 20 mg i.m. It is FDA approved for the treatment of gastroesophageal reflux disease (GERD) and is also used off-label for a variety of other gastrointestinal disorders. Child dose by weight = (mg/day) = Adult Dose in mg/kg or mg/kg/day x Child Weight in kg OR As 1.0 mg/kg may be more efficacious in some, the dosage may require individualization based on response. Adult Dosing . The dosage of famotidine in patients with pathological hypersecretory conditions varies with the individual patient. Prior to treatment and 30 min after treatment, patients rated pruritus and sedation using visual analogue scales, while physicians . Adult: Not defined; Pediatric:Not defined; Contraindications. (65% to 70%) of a famotidine dose is excreted in the urine; 30% to 35% of the dose is metabolized by the liver. Dosage. What is this drug used for? Dose: 0.5 mg/kg orally twice daily; Nizatidine (Axid) 15 mg/ml. Consider treatment with H2RA or PPI (see Tier 3 for PPI dosages). Treat for 6 to 12 weeks. This should not be used in newborns or in pregnant women unless in a single-dose vial. Proposed daily dosage in NCT04370262 is 9 times the usual manufacturer-recommended IV adult dosage; the study excludes patients with creatinine clearance (Clcr) 50 mL/minute, including dialysis patients . To treat erosive esophagitis (heartburn): Adults and children weighing 40 kilograms (kg) or more20 milligrams (mg) 1 or 2 times per day, at the morning and at bedtime, or 40 mg once a day at bedtime for up to 12 weeks. renal dosing [see below] CrCl 30-50: give usual divided dose q24h; CrCl 10-29: give 50% usual divided dose q24h; CrCl 10: give 25% usual divided dose q24h HD: give 25% usual divided dose q24h, on dialysis days admin. Dosage Adjustments for Patients with Moderate or Severe Renal Insufficiency. The studies described in PRECAUTIONS, Pediatric Patients <1 year of age suggest the following starting doses in pediatric patients<1 year of age: Gastroesophageal Reflux Disease (GERD) - 0.5 mg/kg/dose of famotidine oral suspension for the treatment of GERD for up to 8 weeks once daily in patients <3 months of age and 0.5 mg/kg/dose twice daily . . Children 12 years or older: 10-20 mg every 12 hours, may take 15-60 min before eating foods that could cause heartburn. Table 2: Recommended Maximum Dosage of Famotidine Tablets in Adults and Pediatric Patients 40 kg and Greater with Moderate and Severe Renal Impairment Indication Creatinine clearence 30 to 60mL/minute Creatinine clearence less than 30 mL/minute Active duodenal ulcer (DU) 20mg once daily; or 40mg every other day 20mg every other day a Children weighing less than 40 kgUse and dose be determined by your doctor. Famotidine is being given IV in 120-mg doses three times daily for a maximum of 14 days or until hospital discharge, whichever comes first. 10-20 mg every 12 hours, it may take 15-60 min before eating foods that could cause heartburn. While famotidine may be effective in patients with less severe GERD, proton pump inhibitors (PPIs) offer more rapid symptom relief and better healing.